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KMID : 0191120220370100080
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Journal of Korean Medical Science
2022 Volume.37 No. 10 p.80 ~ p.80
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A Retrospective Population-Based Survival Study of Idiopathic Pulmonary Arterial Hypertension in Korea
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Jang Shin-Yi
Kim Eun-Kyoung
Huh June
Song Jin-Young
Kang I-Seok
Park Seung-Woo
Kim Duk-Kyung
Chang Sung-A
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Abstract
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Background: Few studies used nationwide data to assess the survival rates (SRs) and death risk for idiopathic pulmonary arterial hypertension (IPAH; ICD-10 I27.0) in Korea.
Methods: IPAH data (N = 9,017; female:male = 6:4) were collected from the National Health Insurance Service in Korea, from 2006 through 2017. The data consisted of primary diagnoses related to IPAH. The Kaplan?Meier method and Cox proportional-hazards analyses were carried out.
Results: The mean age was 62.3 (± 19.4) years, 64.2 (± 18.9) years in female and 59.4 (± 19.8) years in male (P < 0.001). The one-, three-, five- and 10-year SRs for IPAH were 89.0%, 79.8%, 72.3% and 57.0%, respectively. The adjusted hazard ratio (HR) of IPAH was 1.81 (95% confidence interval [CI], 1.26?2.59) in 60?69 age group, 3.42 (95% CI, 2.40?4.87) in 70?79, and 7.73 (95% CI, 5.43?11.0) in 80s. Other risk factors were male, low-income status, diabetes, myocardial infarction, atrial fibrillation, ischemic stroke, hemorrhagic stroke, and malignant neoplasm.
Conclusion: The 10-year SR of IPAH was 57% in Korea. The HR for IPAH was significantly high in patients with older age and other risk factors.
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KEYWORD
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Survival Rates, Death, Risk, Causes of Death, Idiopathic Pulmonary Arterial Hypertension
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